The UK & International Peptide Index &
Analytical Chemical Directory.

BPC-157 is a 15-amino-acid synthetic peptide derived from human gastric juice protein BPC. Preclinical laboratory models investigate its interaction with focal adhesion kinase (FAK), vascular endothelial growth factor receptor 2 (VEGFR2), and early growth response protein 1 (egr-1).

TB-500 is a synthetic peptide containing the primary active actin-sequestering domain of naturally occurring Thymosin Beta-4. Preclinical investigations focus on its ability to regulate G-actin polymerization, promote cellular migration, and attenuate cardiac and myofibrillar fibrotic scarring.

Semax is a synthetic heptapeptide structurally related to the 4-10 fragment of adrenocorticotropic hormone (ACTH), stabilized by a C-terminal Pro-Gly-Pro tripeptide. It lacks hormonal endocrine activity while displaying neurotrophic and neuroprotective properties in cerebral ischemia assays.

GHK-Cu is a human plasma-derived tripeptide with stoichiometric affinity for copper(II) ions. Researched for its capacity to modulate gene expression involved in tissue remodeling, upregulate procollagen and elastin biosynthesis, and stimulate in vitro dermal fibroblast migration.

CJC-1295 is a tetrasubstituted 29-amino-acid synthetic peptide analog of growth hormone-releasing hormone (GHRH). It is designed with substitutions at positions 2, 8, 15, and 27 to impart resistance against dipeptidyl peptidase-4 (DPP-4) enzymatic degradation.

Ipamorelin is a synthetic pentapeptide and selective ghrelin/growth hormone secretagogue receptor 1a (GHSR-1a) agonist. It demonstrates exquisite somatotroph selectivity, eliciting endogenous growth hormone pulses without significantly raising adrenocorticotropic hormone (ACTH), cortisol, prolactin, or aldosterone.

AOD-9604 is a synthetic 16-amino-acid peptide fragment corresponding to the lipolytic C-terminus of human growth hormone (hGH 177-191) with an added N-terminal tyrosine residue. Studied for its capacity to stimulate beta-3 adrenergic lipolytic pathways without affecting insulin sensitivity or serum IGF-1 levels.

Selank is a synthetic regulatory heptapeptide derived from the immunomodulatory tetrapeptide tuftsin with a C-terminal Pro-Gly-Pro sequence extension. Investigated in neurochemical models for allosteric GABA-A receptor modulation, enkephalinase inhibition, and brain-derived neurotrophic factor (BDNF) mRNA expression.

Epithalon is a synthetic biomimetic tetrapeptide modeled after the endogenous pineal peptide epithalamin. Investigated for its ability to induce telomerase reverse transcriptase (TERT) expression, elongate telomeres in human somatic cells, modulate melatonin synthesis, and reduce oxidative mitochondrial stress.

MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S ribosomal RNA. Investigated in metabolic and biogerontology models for its ability to translocate to the nucleus under metabolic stress, activate AMPK (5′ AMP-activated protein kinase), and regulate nuclear gene expression related to glucose utilization and cellular senescence.

Tirzepatide is a 39-amino-acid synthetic peptide engineered with dual agonism at both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. Investigated in extensive clinical trials and preclinical pharmacological assays for glucose homeostasis, lipolytic modulation, and pancreatic beta-cell insulin secretion.

Semaglutide is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist modified with an alpha-aminoisobutyric acid substitution and a C-18 fatty diacid spacer to facilitate non-covalent albumin binding. Characterized across human clinical trials for glucose regulation and neuro-endocrine appetite pathway interactions.